09.24.12 – 09.26.12
May 11, 2012SMi’s Biosimilars and Biobetters (David E. Szymkowski, Ph.D., presenting; London, UK)
Posted in EVENTS | Comments OffXencor Receives Milestone Payment from CSL Limited Under Antibody Optimization Collaboration
April 19, 2012SEVENTH ANTIBODY DEVELOPED WITH XENCOR’S XmAb TECHNOLOGY MOVES INTO HUMAN TRIALS MONROVIA, Calif., April 19, 2012 – Xencor, Inc. announced today that the Company received a milestone payment under an antibody optimization collaboration agreement with CSL Limited. The payment was … …
Posted in PRESS RELEASES | Comments Off05.20.12 – 05.23.12
April 9, 20124th DIA China Annual Meeting (Bassil Dahiyat, Ph.D., Speaker; Shanghai, China)
Posted in EVENTS | Comments OffXencor Receives Second Milestone Payment from Boehringer Ingelheim Under Antibody Technology License Agreement
April 4, 2012MONROVIA, Calif., April 4, 2012 – Xencor, Inc. announced today that the Company received a milestone payment under a technology license agreement with Boehringer Ingelheim. The payment was triggered by a regulatory submission to begin Phase 1 clinical trials of … …
Posted in PRESS RELEASES | Comments Off03.26.12 – 03.28.12
March 13, 201224th Annual EuroMeeting, Drug Information Association (David Szymkowski, Ph.D., presenting; Copenhagen, Denmark)
Posted in EVENTS | Comments Off03.25.12 – 03.30.12
March 12, 2012Gordon Research Conference – Antibody Biology & Engineering (John Desjarlais, Ph.D., presenting; Galveston, TX)
Posted in EVENTS | Comments Off03.19.12 – 03.22.12
March 11, 2012IBC’s 3rd Biotherapeutics Analytical Summit (David Szymkowski, Ph.D., presenting; Baltimore, MD)
Posted in EVENTS | Comments Off02.29.12 – 03.02.12
February 29, 2012IBC’s 28th International Antibody Development & Production (David Szymkowski, Ph.D., presenting; San Diego, CA)
Posted in EVENTS | Comments Off02.29.12 – 03.02.12
February 29, 2012Biobetters & Biosimilars – Technologies & Development Strategies (Bassil Dahiyat, Ph.D., presenting; San Diego, CA)
Posted in EVENTS | Comments OffBoehringer Ingelheim and Xencor Enter a Collaboration Agreement for the Development, Manufacture, and Supply of Biosuperior Monoclonal Antibodies
February 21, 2012Antibodies engineered with Xencor’s proprietary Xtend™ technology for increasing antibody half-life MONROVIA, Calif., USA and INGELHEIM, Germany – February 21, 2012 – Xencor, Inc., a company using its proprietary Protein Design Automation® (PDA) platform technology to engineer next-generation antibodies, and … …
Posted in PRESS RELEASES | Comments Off01.30.12 – 01.31.12
January 30, 20124th Immunotherapeutics and Immunomonitoring Conference (John Desjarlais, Ph.D., presenting; San Diego, CA)
Posted in EVENTS | Comments Off01.30.12 – 01.31.12
January 30, 2012Allergy Drug Discovery and Development Conference (Bassil Dahiyat, Ph.D., presenting; San Diego, CA)
Posted in EVENTS | Comments OffTai YT, Horton HM, Kong SY, Pong E, Chen H, Cemerski S, Bernett MJ, Nguyen DH, Karki S, Chu SY, Lazar GA, Munshi NC, Desjarlais JR, Anderson KC, Muchhal US (2012)
January 23, 2012Potent in vitro and in vivo activity of an Fc-engineered humanized anti-HM1.24 antibody against multiple myeloma via augmented effector function. Blood. 2012 Jan 13. [Epub ahead of print]
Posted in PUBLICATIONS | Comments OffChu SY, Horton H, Pong E, Leung I, Chen H, Nguyen D-H, Bautista C, Muchhal US, Bernett M, Moore GL, Szymkowski DE, Desjarlais JR (2012)
January 23, 2012Reduction of Total IgE by Targeted Coengagement of IgE B cell Receptor and FcgRIIb with Fc-Engineered Antibody. J Allergy Clin Immunol, doi:10.1016/j.jaci.2011.11.029
Posted in PUBLICATIONS | Comments OffCemerski S, Chu SY, Moore GL, Muchhal US, Desjarlais JR, Szymkowski DE (2012)
January 23, 2012Suppression of mast cell degranulation through a dual-targeting tandem IgE-IgG Fc domain biologic engineered to bind with high affinity to FcgRIIb. Immunol Lett, in press.
Posted in PUBLICATIONS | Comments Off01.11.12 – 01.12.12
January 11, 2012Antibodies for the 21st Century (John Desjarlais, Ph.D., presenting; San Diego, CA)
Posted in EVENTS | Comments OffMoore GL, Bautista C, Pong E, Nguyen DH, Jacinto J, Eivazi A, Muchhal US, Karki S, Chu SY, Lazar GA (2011)
December 30, 2011A novel bispecific antibody format enables simultaneous bivalent and monovalent co-engagement of distinct target antigens. MAbs. Nov 1;3(6). [Epub ahead of print].
Posted in PUBLICATIONS | Comments Off12.04.11 – 12.08.11
December 4, 2011Antibody Engineering and Antibody Therapeutics (John Desjarlais, Ph.D., San Diego, CA)
Posted in EVENTS | Comments OffXencor Initiates Phase 1 Study of XmAb®5871 Therapeutic Antibody For the Treatment of Autoimmune Diseases; Dual-Targeted Antibody Aims to Treat Lupus and Rheumatoid Arthritis by Suppressing Autoimmune Response
October 21, 2011Xencor, Inc., a company using its proprietary Protein Design Automation® (PDA) platform technology to engineer next-generation antibodies, announced today the initiation of a Phase 1 clinical trial of XmAb®5871, the company’s therapeutic antibody for the treatment of autoimmune diseases. …
Posted in PRESS RELEASES | Comments Off11.04.11 – 11.09.11
September 21, 2011American College of Rheumatology Annual Scientific Meeting (Matthew Bernett, Ph.D., presenting; Chicago, IL)
Posted in EVENTS | Comments OffJR Desjarlais and GA Lazar (2011)
August 5, 2011Modulation of antibody effector function. Experimental Cell Research 317(9)1278-1285 …
Posted in PUBLICATIONS | Comments Off10.11.11 – 10.13.11
June 17, 2011PEGS Europe – Protein & Antibody Engineering Summit (John Desjarlais, Ph.D., presenting; Hannover, Germany)
Posted in EVENTS | Comments Off08.01.11 – 08.03.11
June 17, 2011Drug Discovery & Diagnostic Development (John Desjarlais, Ph.D., presenting; San Francisco, CA)
Posted in EVENTS | Comments Off06.27.11 – 06.30.11
May 23, 20112011 BIO International Convention (Bassil I. Dahiyat, Ph.D.; Washington, D.C.)
Posted in EVENTS | Comments Off09.03.11 – 09.06.11
May 23, 2011IMPULSE 2011: Immune-related Pathologies: Understanding Leukocyte Signaling and Emerging Therapies (David E. Szymkowski, Ph.D., presenting; Visegrád, Hungary)
Posted in EVENTS | Comments Off